Vinpocetine attenuates lipid accumulation and atherosclerosis formation
نویسندگان
چکیده
منابع مشابه
Activation of TRPV1 reduces vascular lipid accumulation and attenuates atherosclerosis.
AIMS Activation of transient receptor potential vanilloid type-1 (TRPV1) channels may affect lipid storage and the cellular inflammatory response. Now, we tested the hypothesis that activation of TRPV1 channels attenuates atherosclerosis in apolipoprotein E knockout mice (ApoE(-/-)) but not ApoE(-/-)TRPV1(-/-) double knockout mice on a high-fat diet. METHODS AND RESULTS Both TRPV1 mRNA and pr...
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ژورنال
عنوان ژورنال: Biochemical and Biophysical Research Communications
سال: 2013
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2013.03.092